×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Exon eight APC mutations account for a disproportionate number of familial adenomatous polyposis families.
8118461 1994
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Unexplained polyposis: a challenge for geneticists, pathologists and gastroenterologists.
21476993 2012
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Familial adenomatous polyposis (FAP ) is caused by germline mutations in the adenomatous polyposis coli (APC ) gene.21643010 2011
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Familial adenomatous polyposis : aberrant splicing due to missense or silent mutations in the APC gene.15459959 2004
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Eight novel inactivating germ line mutations at the APC gene identified by denaturing gradient gel electrophoresis.
1324223 1992
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Mutational analysis of patients with adenomatous polyposis: identical inactivating mutations in unrelated individuals.
8381579 1993
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Dominant negative effect of the APC1309 mutation: a possible explanation for genotype-phenotype correlations in familial adenomatous polyposis.
10213492 1999
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
APC mutation spectrum of Norwegian familial adenomatous polyposis families: high ratio of novel mutations.
19444466 2009
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Screening for mutations of the APC gene in 66 Italian familial adenomatous polyposis patients: evidence for phenotypic differences in cases with and without identified mutation.
10094547 1999
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312 2016
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Activating mutation in MET oncogene in familial colorectal cancer.
21970370 2011
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
A survey of APC mutations in Quebec.
21779980 2011
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
APC gene mutations causing familial adenomatous polyposis in Polish patients.
19029688 2008
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Pathogenic mutations and rare variants of the APC gene identified in 75 Belgian patients with familial adenomatous polyposis by fluorescent enzymatic mutation detection (EMD).
12173026 2002
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.
1316610 1992
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.
25980754 2015
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Attenuated familial adenomatous polyposis (AFAP). A phenotypically and genotypically distinctive variant of FAP.
8625067 1995
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Genotype-phenotype correlations in attenuated adenomatous polyposis coli.
9585611 1998
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Familial adenomatous polyposis: more evidence for disease diversity and genetic heterogeneity.
11247895 2001
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
A comparison of the phenotype and genotype in adenomatous polyposis patients with and without a family history.
15951963 2005
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Singapore familial adenomatous polyposis (FAP) patients with classical adenomatous polyposis but undetectable APC mutations have accelerated cancer progression.
17026565 2006
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas.
19793053 2009
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Initial results of colorectal polyposis research in Latvia.
19331226 2009
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
We screened the entire coding region of the APC gene for mutations in an unselected series of 105 Dutch FAP kindreds.
8990002 1997
×
Entrez Id: 324
Gene Symbol: APC
APC
Adenomatous Polyposis Coli
1.000
CausalMutation
CLINVAR
Germline APC mutation spectrum derived from 863 genomic variations identified through a 15-year medical genetics service to French patients with FAP.
20685668 2010